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complex(g(HGNC:MIR384), r(HGNC:BACE1))

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Components

Appears in Networks 1

New insights into the role of microRNAs and long noncoding RNAs in most common neurodegenerative diseases v1.0.0

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Out-Edges 3

complex(g(HGNC:MIR384), r(HGNC:BACE1)) hasComponent g(HGNC:MIR384) View Subject | View Object

Appears in Networks:

complex(g(HGNC:MIR384), r(HGNC:BACE1)) hasComponent r(HGNC:BACE1) View Subject | View Object

Appears in Networks:

complex(g(HGNC:MIR384), r(HGNC:BACE1)) decreases p(HGNC:BACE1) View Subject | View Object

It was found that miR‐384, by binding to the 3′‐UTR sequence on BACE1 mRNA, could not only reduce expression in SH‐SY5Y cells but also attach to the 3′‐UTR sequence of the mRNA APP and reduce its expression, and this highlights the importance of miR‐384 in AD PubMed:30663117

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
SH-SY5Y
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.