act(complex(GO:"proteasome complex")) negativeCorrelation a(GO:"neurofibrillary tangle")

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PubMed:22908190

That is, in areas where NFTs formed abundantly, including hippocampus and parahippocampal gyrus and superior and middle temporal gyri, proteasome activity (as assessed by chymortrypsinlike and postglutamyl peptidases) appeared to be most affected, whereas occipital gyri and cerebellum, which often have few or no NFTs, were least affected (Keller et al. 2000).

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• a(GO:"neurofibrillary tangle") negativeCorrelation act(complex(GO:"proteasome complex"))

MeSH

Hippocampus

MeSH

Parahippocampal Gyrus

MeSH

Temporal Lobe

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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