Appears in Networks 1

Provenance

PubMed:22299660

Decreased mRNA levels of PP2A C have been reported in the CA3 region of AD hippocampus by in situ RNA hybridisation [56]. Moreover, microarray RNA analysis carried out to compare the expression of more than 7,000 gene in the amygdala, cingulate cortex, striatum and cerebellum dis- closed down-regulation of the catalytic subunit PP2A C in AD [57]. This has been further corroborated by quantitative TaqMan PCR showing reduced PP2A C mRNA expression levels in the hippocampus, but not in the frontal cortex, in AD cases with disease progression Fig. (1).

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.