composite(a(CHEBI:"dasatinib (anhydrous)"), a(CHEBI:quercetin)) decreases a(GO:"neurofibrillary tangle")

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PubMed:30126037

The astrocyte protein GFAP was unchanged, while microglia Iba1 expression was elevated (Iba1: 40%, P = 0.0013; Figure S6b-d) suggesting that DQ-mediated neuroprotection and decreased SASP was not derived from a reduction in pro-inflammatory glia (astrocytes or microglia) but instead associated with fewer NFT-containing neurons

Related Edges 3

• composite(a(CHEBI:"dasatinib (anhydrous)"), a(CHEBI:quercetin)) decreases bp(GO:"cellular senescence")
• composite(a(CHEBI:"dasatinib (anhydrous)"), a(CHEBI:quercetin)) increases p(MGI:Aif1)
• composite(a(CHEBI:"dasatinib (anhydrous)"), a(CHEBI:quercetin)) increases bp(MESH:Neuroprotection)

Confidence

High

MeSH

Neurons

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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