a(CHEBI:Anatabine) decreases bp(GO:"macrophage activation")

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PubMed:22807490

Anatabine suppressed in a dose- dependent manner the increase of iNOS and COX2 in- duced by interferon-g (Fig.4),confirming in vitro its antiinflammatory properties. The effect seen with inter- feron-g was also seen when macrophages were stimulated with lipopolysaccharide (Supplemental Fig. 1).

Related Edges 5

• a(CHEBI:Anatabine) decreases p(HGNC:NOS2)
• a(CHEBI:Anatabine) decreases p(HGNC:PTGS2)
• a(CHEBI:lipopolysaccharide) increases bp(GO:"macrophage activation")
• p(HGNC:IFNG) increases p(HGNC:NOS2)
• p(HGNC:IFNG) increases p(HGNC:PTGS2)

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