bp(MESH:"Cytotoxicity, Immunologic") positiveCorrelation a(CHEBI:"iron(2+)")

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PubMed:25307023

Thus, by participating in Fenton chemistry, non-transferrin-bound iron (i.e., iron not bound to the physiological iron transport protein, transferrin) causes oxidative damage, cytotoxicity and enhanced endothelial expression of adhesion molecules, thereby enhancing thrombotic risk (Hershko, 2007).

Related Edges 5

• a(CHEBI:"iron(2+)") positiveCorrelation bp(MESH:"Oxidative Stress")
• a(CHEBI:"iron(2+)") positiveCorrelation bp(MESH:"Cytotoxicity, Immunologic")
• a(CHEBI:"iron(2+)") increases a(MESH:"Cell Adhesion Molecules")
• a(CHEBI:"iron(2+)") increases path(MESH:Thrombosis)
• bp(MESH:"Oxidative Stress") positiveCorrelation a(CHEBI:"iron(2+)")

Cell Ontology (CL)

endothelial cell

MeSH

Plasma

MeSH

Urine

MeSH

Anemia, Hemolytic, Autoimmune

Text Location

Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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