a(HBP:"6-O-sulfated heparin") positiveCorrelation complex(a(HBP:"6-O-sulfated heparin"), a(HBP:"Tau isoform F (441 aa)"))
Removal of N-sulfates or 2-O-sulfates had little effect on tau binding (15.0 ± 5 nM and 7.4 ± 1.0 nM, respectively), while removal of all O-sulfates and, in particular 6-O-sulfates, led to a significant decrease in tau binding (>1 μM in each case; Fig. 3c,d)
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.