bp(MESH:Phagocytosis) negativeCorrelation bp(GO:"actin cytoskeleton reorganization")

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PubMed:27798618

We quantified these changes by automatic image analysis and found that heme-induced cytoskeleton rearrangement led to a significant increase in cell area and perimeter, as well as a decrease in circularity (form factor) (Fig. 4d,e and Supplementary Fig. 3b–d), indicating that the heme-induced defective phagocytic response was likely tied to cytoskeleton rearrangements.

Related Edges 3

• a(CHEBI:heme) positiveCorrelation bp(GO:"actin cytoskeleton reorganization")
• bp(GO:"actin cytoskeleton reorganization") positiveCorrelation a(CHEBI:heme)
• bp(GO:"actin cytoskeleton reorganization") negativeCorrelation bp(MESH:Phagocytosis)

Cell Ontology (CL)

monocyte

MeSH

Blood

MeSH

Sepsis

Text Location

Results

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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