visual cortex

Name: visual cortex
Namespace Keyword: Anatomy
Namespace: Uberon
Namespace Version: 20170511
Namespace URL: https://arty.scai.fraunhofer.de/artifactory/bel/annotation/anatomy/anatomy-20170511.belanno

Sample Annotated Edges 1

complex(GO:"neurofibrillary tangle") causesNoChange act(a(MESH:Neurons)) View Subject | View Object

We found that in the visual cortex, neurons containing conspicuous quantities of mislocalized and aggregated tau nonetheless appear to have a normal capacity to integrate dendritic inputs and respond robustly to visual stimuli and also maintain normal somatic baseline calcium levels. In particular, we show that individual NFT-bearing neurons can respond robustly after integrating sensory inputs and are functionally indistinguishable from neighboring non–NFT-bearing neurons. These results demonstrate that NFT-bearing neurons remain functionally integrated in cortical circuits. PubMed:24368848

Appears in Networks:

Tau Biochemistry v1.2.5

Annotations

Uberon: visual cortex
MeSH: Frontotemporal Dementia

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.