Name
Axons
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

p(HGNC:APP) association bp(GO:"protein transport") View Subject | View Object

A role for APP has been suggested in neurite outgrowth and synaptogenesis, neuronal protein trafficking along the axon, transmembrane signal transduction, cell adhesion, calcium metabolism, etc, all requiring additional in vivo evidence (reviewed in [19]) PubMed:21214928

Annotations
Confidence
High
MeSH
Axons
MeSH
Neurons

bp(GO:"protein transport") association p(HGNC:APP) View Subject | View Object

A role for APP has been suggested in neurite outgrowth and synaptogenesis, neuronal protein trafficking along the axon, transmembrane signal transduction, cell adhesion, calcium metabolism, etc, all requiring additional in vivo evidence (reviewed in [19]) PubMed:21214928

Annotations
Confidence
High
MeSH
Axons
MeSH
Neurons

p(FPLX:CHRN) regulates bp(GO:"rhythmic excitation") View Subject | View Object

Furthermore, by directly exciting or by shunting the progress of an action potential at a bifurcation, axonal or dendritic nAChRs alter the spread of neuronal excitation. PubMed:17009926

p(HBP:"Tau isoform B (381 aa)", pmod(HBP:"protein aggregation")) decreases bp(GO:"anterograde axonal transport") View Subject | View Object

Similarly, perfusion of squid axoplasms with hT39, hT37 and hT23 aggregates significantly impaired anterograde FAT (Fig. 4A) when compared to the respective monomers (all at 2 μM) PubMed:27574109

p(HBP:"Tau isoform C (410 aa)", pmod(HBP:"protein aggregation")) decreases bp(GO:"anterograde axonal transport") View Subject | View Object

Similarly, perfusion of squid axoplasms with hT39, hT37 and hT23 aggregates significantly impaired anterograde FAT (Fig. 4A) when compared to the respective monomers (all at 2 μM) PubMed:27574109

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.