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Entity

Name
protein transport
Namespace
go
Namespace Version
20181221
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/73688d6dc24e309fca59a1340dc9ee971e9f3baa/external/go-names.belns

Appears in Networks 2

In-Edges 6

p(HGNC:APP) association bp(GO:"protein transport") View Subject | View Object

A role for APP has been suggested in neurite outgrowth and synaptogenesis, neuronal protein trafficking along the axon, transmembrane signal transduction, cell adhesion, calcium metabolism, etc, all requiring additional in vivo evidence (reviewed in [19]) PubMed:21214928

Annotations
Confidence
High
MeSH
Axons
MeSH
Neurons

p(HGNC:APP) regulates bp(GO:"protein transport") View Subject | View Object

Overall, most studies suggest that APP plays some role in regulating protein trafficking PubMed:21214928

Annotations
Confidence
High
MeSH
Neurons

complex(p(HGNC:APBA1), p(HGNC:APP)) regulates bp(GO:"protein transport") View Subject | View Object

For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165] PubMed:21214928

complex(p(HGNC:APBA2), p(HGNC:APP)) regulates bp(GO:"protein transport") View Subject | View Object

For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165] PubMed:21214928

complex(p(HGNC:APBA3), p(HGNC:APP)) regulates bp(GO:"protein transport") View Subject | View Object

For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165] PubMed:21214928

p(FPLX:HSP90) association bp(GO:"protein transport") View Subject | View Object

Accordingly, Hsp90 affects many key cellular processes, including cell cycle progression, steroid signaling, calcium signaling, protein trafficking, protein secretion, the immune re- sponse, and the heat shock response (HSR) (45, 48, 82). PubMed:23746257

Out-Edges 2

bp(GO:"protein transport") association p(HGNC:APP) View Subject | View Object

A role for APP has been suggested in neurite outgrowth and synaptogenesis, neuronal protein trafficking along the axon, transmembrane signal transduction, cell adhesion, calcium metabolism, etc, all requiring additional in vivo evidence (reviewed in [19]) PubMed:21214928

Annotations
Confidence
High
MeSH
Axons
MeSH
Neurons

bp(GO:"protein transport") association p(FPLX:HSP90) View Subject | View Object

Accordingly, Hsp90 affects many key cellular processes, including cell cycle progression, steroid signaling, calcium signaling, protein trafficking, protein secretion, the immune re- sponse, and the heat shock response (HSR) (45, 48, 82). PubMed:23746257

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.