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Ependyma

Name
Ependyma
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

a(CHEBI:"desferrioxamine B") negativeCorrelation path(MESH:Hydrocephalus) View Subject | View Object

Coinjection of deferoxamine with lysed RBC reduced ventricular enlargement (47.8±17.8 vs. 59.9±15.7mm3 in saline coinjection group, Po0.05, Figure 6). PubMed:24667910

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Ependyma
Text Location
Results

a(CHEBI:"desferrioxamine B") negativeCorrelation path(MESH:Hydrocephalus) View Subject | View Object

The major findings of this study are (1) intraventricular injection of lysed RBCs but not packed RBCs resulted in hydrocephalus; (2) lysed RBCs upregulated brain HO-1 and ferritin levels; (3) intraventricular injection of iron also caused hydrocephalus; and (4) iron chelation with deferoxamine reduced lysed RBC-induced hydrocephalus. PubMed:24667910

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Ependyma
Text Location
Discussion

a(CHEBI:"desferrioxamine B") negativeCorrelation path(MESH:"Brain Edema") View Subject | View Object

There was a tendency that lysed RBC-induced brain edema was less in deferoxamine-treated group (brain water content in the ipsilateral hemisphere: 79.8±0.6% vs. 80.5±0.7% in the saline coinjection group, n¼6, P40.05). PubMed:24667910

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Ependyma
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a(CHEBI:"iron(2+)") positiveCorrelation path(HP:"Intraventricular hemorrhage") View Subject | View Object

In addition, iron and ferritin deposition are found in ependymal or subependymal location after neonatal IVH.7–9 PubMed:24667910

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Ependyma
Text Location
Introduction

a(CHEBI:"iron(2+)") positiveCorrelation path(MESH:Hydrocephalus) View Subject | View Object

Twenty-four hours after injection, T2 MRI showed a significant bilateral ventricular enlargement in the iron-injected group (17.9±5.7mm3) compared with salineinjected rats (9.2±5.7mm3, Po0.01, Figure 4). PubMed:24667910

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MeSH
Ependyma
Text Location
Results

Showing 5 of 31 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.