1. Catalog
  2. Namespaces
  3. MeSH
  4. Neck

Neck

Name
Neck
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Parenchymal Tissue"), toLoc(MESH:"Lymph Nodes")) View Subject | View Object

These findings, as has been suggested previously, demonstrate that the efflux of parenchymal and/or ISF macromolecules and the drainage of these macromolecules into dCLNs are impaired as a consequence of meningeal lymphatic ablation, thus functionally connecting meningeal lymphatics with CSF influx and ISF efflux mechanisms PubMed:30046111

Appears in Networks:
Annotations
Confidence
High
MeSH
Meninges
MeSH
Neck

p(MGI:Vegfc) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes")) View Subject | View Object

Accordingly, the drainage of CSF macromolecules into dCLNs was significantly higher in sham-operated mice treated with mVEGF-C compared to all other groups (Fig. 2s, t) PubMed:30046111

Appears in Networks:
Annotations
Confidence
High
MeSH
Neck

a(MESH:"Lymphatic Vessels") increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes")) View Subject | View Object

Here we show that meningeal lymphatic vessels have an essential role in maintaining brain homeostasis by draining macromolecules from the CNS (both CSF and ISF) into the cervical lymph nodes PubMed:30046111

Appears in Networks:
Annotations
Confidence
High
MeSH
Meninges
MeSH
Neck

act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(HP:"interstitial fluid"), toLoc(MESH:"Lymph Nodes")) View Subject | View Object

These findings, as has been suggested previously, demonstrate that the efflux of parenchymal and/or ISF macromolecules and the drainage of these macromolecules into dCLNs are impaired as a consequence of meningeal lymphatic ablation, thus functionally connecting meningeal lymphatics with CSF influx and ISF efflux mechanisms PubMed:30046111

Appears in Networks:
Annotations
Confidence
High
MeSH
Meninges
MeSH
Neck

a(MESH:"Lymph Nodes") decreases a(CHEBI:"amyloid-beta") View Subject | View Object

A study suggested that Aβ is removed from CSF to cervical lymph nodes via perineural space of the olfactory nerve (Picken 2001; Pollay 2010) PubMed:29626319

Appears in Networks:
Annotations
MeSH
Neck

Showing 5 of 7 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.