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Appears in Networks 1

In-Edges 1

complex(p(HGNC:NFKB1), p(HGNC:RELA)) increases complex(p(HGNC:BACE1), p(HGNC:NFKB1), p(HGNC:RELA)) View Subject | View Object

The binding of p65/p50 or p65/p52 NF- κB heterodimer in the BACE1 promoter results in transcriptional activation whereas the binding of c-Rel/p52 heterodimer results in repression of BACE1 transcription PubMed:28745240

Out-Edges 4

complex(p(HGNC:BACE1), p(HGNC:NFKB1), p(HGNC:RELA)) increases p(HGNC:BACE1) View Subject | View Object

The binding of p65/p50 or p65/p52 NF- κB heterodimer in the BACE1 promoter results in transcriptional activation whereas the binding of c-Rel/p52 heterodimer results in repression of BACE1 transcription PubMed:28745240

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.