1. Catalog
  2. Nodes
  3. a(MESH:"Reactive Nitrogen Species")

a(MESH:"Reactive Nitrogen Species")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Reactive Nitrogen Species
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

a(CHEBI:"3-nitrotyrosine") positiveCorrelation a(MESH:"Reactive Nitrogen Species") View Subject | View Object

Protein tyrosine nitration has been identified as a biomarker of oxidative stress, and the generation of 3-nitrotyrosine (3-NT) is often accompanied with the increasing of ROS and RNS under pathologic condition [14]. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Results

bp(MESH:Apoptosis) positiveCorrelation a(MESH:"Reactive Nitrogen Species") View Subject | View Object

Apoptosis has been found to be a major rout for the elimination of cells after a variety of stresses including ROS and RNS [30]. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Results

p(HGNC:ALB, var("tyr")) decreases act(a(MESH:"Reactive Nitrogen Species")) View Subject | View Object

Furthermore, the cytoprotective effect of BSA was stronger than that of BSA-T (Fig. 5), suggesting that tyrosine residues of BSA act as oxidation target to prevent other important protein from heme-induced RNS associated damage. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Discussion

Out-Edges 2

a(MESH:"Reactive Nitrogen Species") positiveCorrelation bp(MESH:Apoptosis) View Subject | View Object

Apoptosis has been found to be a major rout for the elimination of cells after a variety of stresses including ROS and RNS [30]. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Results

a(MESH:"Reactive Nitrogen Species") positiveCorrelation a(CHEBI:"3-nitrotyrosine") View Subject | View Object

Protein tyrosine nitration has been identified as a biomarker of oxidative stress, and the generation of 3-nitrotyrosine (3-NT) is often accompanied with the increasing of ROS and RNS under pathologic condition [14]. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.