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p(HGNC:ALB, var("tyr"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
ALB
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

p(HGNC:ALB) hasVariant p(HGNC:ALB, var("tyr")) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HGNC:ALB, var("tyr")) decreases path(HM:"Heme cytotoxicity") View Subject | View Object

This result suggested that tyrosine residues of BSA may play an important role in heme detoxification. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Discussion

p(HGNC:ALB, var("tyr")) decreases act(a(MESH:"Reactive Nitrogen Species")) View Subject | View Object

Furthermore, the cytoprotective effect of BSA was stronger than that of BSA-T (Fig. 5), suggesting that tyrosine residues of BSA act as oxidation target to prevent other important protein from heme-induced RNS associated damage. PubMed:30324533

Appears in Networks:
Annotations
MeSH
Hematoma
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.