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p(HBP:"Tau isoform Fetal-tau (352 aa)", pmod(HBP:hyperphosphorylation))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Tau isoform Fetal-tau (352 aa)
Namespace
HBP
Namespace Version
20190207
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/cf4d8bb88754f036b943b4d94ad96e103dcb7149/export/hbp-names.belns

Appears in Networks 1

Caenorhabditis elegans models of tauopathy v1.0.0

In-Edges 1

p(HBP:"Tau isoform Fetal-tau (352 aa)") hasVariant p(HBP:"Tau isoform Fetal-tau (352 aa)", pmod(HBP:hyperphosphorylation)) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HBP:"Tau isoform Fetal-tau (352 aa)", pmod(HBP:hyperphosphorylation)) decreases bp(GO:locomotion) View Subject | View Object

The transgenic lines exhibited a progressive age-associated Unc phenotype, with or without phospho-mimicking mutations PubMed:29191965

Appears in Networks:

p(HBP:"Tau isoform Fetal-tau (352 aa)", pmod(HBP:hyperphosphorylation)) decreases a(MESH:"Motor Neurons") View Subject | View Object

Only PHP tau expression induced morphologic abnormalities in the motor neurons, but none of the lines developed substantial neurodegeneration PubMed:29191965

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.