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  3. p(INTERPRO:"MAP2/Tau projection")

p(INTERPRO:"MAP2/Tau projection")

Equivalencies: 1 | Classes: 1 | Children: 0 | Explore

Entity

Name
MAP2/Tau projection
Namespace
interpro
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/interpro-names.belns

Appears in Networks 2

Tau Biochemistry v1.2.5

Tau Biochemistry Section of NESTOR

TAU and Interaction Partners v1.2.5

TAU Interactions Section of NESTOR

In-Edges 3

a(HBP:"projection domain") equivalentTo p(INTERPRO:"MAP2/Tau projection") View Subject | View Object

Appears in Networks:

act(complex(GO:"plasma membrane")) negativeCorrelation p(INTERPRO:"MAP2/Tau projection") View Subject | View Object

The results suggest that the amino-terminal fragment suppresses neurite outgrowth by competing for plasma membrane binding. PubMed:12551948

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12

p(HGNC:DCTN1) association p(INTERPRO:"MAP2/Tau projection") View Subject | View Object

We show here for the first time that the N-terminal projection domain of tau binds to the C-terminus of the p150 subunit of the dynactin complex. The sequences of tau encoded by exons 1 and 4, which lie at the tip of the N-terminal projection domain, interact with the C-terminal region of p150. PubMed:8391280

Appears in Networks:

Out-Edges 6

p(INTERPRO:"MAP2/Tau projection") equivalentTo a(HBP:"projection domain") View Subject | View Object

Appears in Networks:

p(INTERPRO:"MAP2/Tau projection") association p(HGNC:DCTN1) View Subject | View Object

We show here for the first time that the N-terminal projection domain of tau binds to the C-terminus of the p150 subunit of the dynactin complex. The sequences of tau encoded by exons 1 and 4, which lie at the tip of the N-terminal projection domain, interact with the C-terminal region of p150. PubMed:8391280

Appears in Networks:

p(INTERPRO:"MAP2/Tau projection") partOf p(HGNC:MAPT) View Subject | View Object

Appears in Networks:

p(INTERPRO:"MAP2/Tau projection") isA p(HGNC:MAPT) View Subject | View Object

Appears in Networks:

p(INTERPRO:"MAP2/Tau projection") decreases bp(GO:"neuron projection development") View Subject | View Object

The results suggest that the amino-terminal fragment suppresses neurite outgrowth by competing for plasma membrane binding. PubMed:12551948

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12

p(INTERPRO:"MAP2/Tau projection") negativeCorrelation act(complex(GO:"plasma membrane")) View Subject | View Object

The results suggest that the amino-terminal fragment suppresses neurite outgrowth by competing for plasma membrane binding. PubMed:12551948

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.