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p(HGNC:DCTN1)

Equivalencies: 0 | Classes: 2 | Children: 0 | Explore

Entity

Name
DCTN1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 3

TAU and Interaction Partners v1.2.5

TAU Interactions Section of NESTOR

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection v1.0.0

Tau in physiology and pathology v1.0.0

In-Edges 3

complex(p(HGNC:DCTN1), p(HGNC:MAPT)) hasComponent p(HGNC:DCTN1) View Subject | View Object

Appears in Networks:

p(INTERPRO:"MAP2/Tau projection") association p(HGNC:DCTN1) View Subject | View Object

We show here for the first time that the N-terminal projection domain of tau binds to the C-terminus of the p150 subunit of the dynactin complex. The sequences of tau encoded by exons 1 and 4, which lie at the tip of the N-terminal projection domain, interact with the C-terminal region of p150. PubMed:8391280

Appears in Networks:

complex(a(GO:microtubule), p(HGNC:DCTN1)) hasComponent p(HGNC:DCTN1) View Subject | View Object

Appears in Networks:

Out-Edges 4

p(HGNC:DCTN1) association p(INTERPRO:"MAP2/Tau projection") View Subject | View Object

We show here for the first time that the N-terminal projection domain of tau binds to the C-terminus of the p150 subunit of the dynactin complex. The sequences of tau encoded by exons 1 and 4, which lie at the tip of the N-terminal projection domain, interact with the C-terminal region of p150. PubMed:8391280

Appears in Networks:

p(HGNC:DCTN1) isA complex(p(HGNC:DCTN1), p(HGNC:MAPT)) View Subject | View Object

Appears in Networks:

p(HGNC:DCTN1) isA p(INTERPRO:"Dynein associated protein") View Subject | View Object

Appears in Networks:

p(HGNC:DCTN1) hasVariant p(HGNC:DCTN1, var("?")) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.