Purpura, Thrombotic Thrombocytopenic

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: Purpura, Thrombotic Thrombocytopenic
Namespace: MeSH
Namespace Version: 20181007
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

p(HGNC:ADAMTS13) negativeCorrelation path(MESH:"Purpura, Thrombotic Thrombocytopenic") View Subject | View Object

Decreased function of this zinc-containing metalloprotease that cleaves VWF is implicated in the pathogenesis of both congenital and sporadic TTP (Furlan et al, 1998). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

Out-Edges 1

path(MESH:"Purpura, Thrombotic Thrombocytopenic") negativeCorrelation p(HGNC:ADAMTS13) View Subject | View Object

Decreased function of this zinc-containing metalloprotease that cleaves VWF is implicated in the pathogenesis of both congenital and sporadic TTP (Furlan et al, 1998). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.