p(HGNC:ADAMTS13)
One mechanism that may contribute to enhanced platelet thrombus formation is inhibition of the metalloprotease ADAMTS13 by free hemoglobin [20]. PubMed:29929138
Decreased function of this zinc-containing metalloprotease that cleaves VWF is implicated in the pathogenesis of both congenital and sporadic TTP (Furlan et al, 1998). PubMed:25307023
Decreased function of this zinc-containing metalloprotease that cleaves VWF is implicated in the pathogenesis of both congenital and sporadic TTP (Furlan et al, 1998). PubMed:25307023
One mechanism that may contribute to enhanced platelet thrombus formation is inhibition of the metalloprotease ADAMTS13 by free hemoglobin [20]. PubMed:29929138
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.