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p(HGNC:HAMP)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
HAMP
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

bp(GO:"iron ion homeostasis") positiveCorrelation p(HGNC:HAMP) View Subject | View Object

The major regulator of iron homeostasis is hepcidin (reviewed by Ganz1), which is directly down-regulated by stimulated activity of erythropoiesis.2 PubMed:28143953

Appears in Networks:
Annotations
Text Location
Introduction

bp(MESH:Erythropoiesis) decreases p(HGNC:HAMP) View Subject | View Object

The major regulator of iron homeostasis is hepcidin (reviewed by Ganz1), which is directly down-regulated by stimulated activity of erythropoiesis.2 PubMed:28143953

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:Hemolysis) positiveCorrelation p(HGNC:HAMP) View Subject | View Object

Our results show that hamp1 levels are significantly elevated in the presence of PHZ but is equivalent in both, WT and DKO fish (S6 Fig). PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

Out-Edges 2

p(HGNC:HAMP) positiveCorrelation bp(GO:"iron ion homeostasis") View Subject | View Object

The major regulator of iron homeostasis is hepcidin (reviewed by Ganz1), which is directly down-regulated by stimulated activity of erythropoiesis.2 PubMed:28143953

Appears in Networks:
Annotations
Text Location
Introduction

p(HGNC:HAMP) positiveCorrelation path(MESH:Hemolysis) View Subject | View Object

Our results show that hamp1 levels are significantly elevated in the presence of PHZ but is equivalent in both, WT and DKO fish (S6 Fig). PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.