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bp(MESH:Erythropoiesis)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Erythropoiesis
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 4

a(CHEBI:"lead nitrate") positiveCorrelation bp(MESH:Erythropoiesis) View Subject | View Object

In stark contrast to Wt mice, there was an exuberant increase (57.9%) in Ter119+ cells in Ko + Pb mice, compared to that in Ko − Pb mice (Figure 3A; P = 0.01), suggesting enhanced medullary erythropoiesis in Ko mice upon Pb(NO3)2 administration. PubMed:25411909

Appears in Networks:
Annotations
MeSH
Serum
Text Location
Results

a(MESH:Reticulocytes) positiveCorrelation bp(MESH:Erythropoiesis) View Subject | View Object

Elevated reticulocytes indicated markedly increased erythropoiesis in Ko mice challenged with Pb.29 PubMed:25411909

Appears in Networks:
Annotations
Text Location
Results

complex(a(MESH:"diferric transferrin"), p(HGNC:TFRC)) increases bp(MESH:Erythropoiesis) View Subject | View Object

The pool of di-ferric Tf binds to erythroid cell transferrin receptor 1 (TfR1) and contributes to erythropoiesis [16]. PubMed:30281034

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
Text Location
Review

path(HP:"Hemolytic anemia") positiveCorrelation bp(MESH:Erythropoiesis) View Subject | View Object

Therefore, hemolytic anemia in CEP mice activates a compensatory stress erythropoiesis with no sign of ineffective erythropoiesis. PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Spleen
MeSH
Porphyria, Erythropoietic
Text Location
Results

Out-Edges 4

bp(MESH:Erythropoiesis) positiveCorrelation a(MESH:Reticulocytes) View Subject | View Object

Elevated reticulocytes indicated markedly increased erythropoiesis in Ko mice challenged with Pb.29 PubMed:25411909

Appears in Networks:
Annotations
Text Location
Results

bp(MESH:Erythropoiesis) positiveCorrelation a(CHEBI:"lead nitrate") View Subject | View Object

In stark contrast to Wt mice, there was an exuberant increase (57.9%) in Ter119+ cells in Ko + Pb mice, compared to that in Ko − Pb mice (Figure 3A; P = 0.01), suggesting enhanced medullary erythropoiesis in Ko mice upon Pb(NO3)2 administration. PubMed:25411909

Appears in Networks:
Annotations
MeSH
Serum
Text Location
Results

bp(MESH:Erythropoiesis) decreases p(HGNC:HAMP) View Subject | View Object

The major regulator of iron homeostasis is hepcidin (reviewed by Ganz1), which is directly down-regulated by stimulated activity of erythropoiesis.2 PubMed:28143953

Appears in Networks:
Annotations
Text Location
Introduction

bp(MESH:Erythropoiesis) positiveCorrelation path(HP:"Hemolytic anemia") View Subject | View Object

Therefore, hemolytic anemia in CEP mice activates a compensatory stress erythropoiesis with no sign of ineffective erythropoiesis. PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Spleen
MeSH
Porphyria, Erythropoietic
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.