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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:"lead nitrate") increases a(MESH:Reticulocytes) View Subject | View Object

Analogous to phenotypic observations of anemia, the percentage of reticulocytes in peripheral blood of Ko + Pb mice was greatly induced by more than 2-fold relative to Ko − Pb mice (P < 0.05) and Wt + Pb mice (P < 0.001) (Figure 2A and B). PubMed:25411909

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bp(MESH:Erythropoiesis) positiveCorrelation a(MESH:Reticulocytes) View Subject | View Object

Elevated reticulocytes indicated markedly increased erythropoiesis in Ko mice challenged with Pb.29 PubMed:25411909

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a(MESH:Reticulocytes) positiveCorrelation bp(MESH:Erythropoiesis) View Subject | View Object

Elevated reticulocytes indicated markedly increased erythropoiesis in Ko mice challenged with Pb.29 PubMed:25411909

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.