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p(HGNC:CHRNA4, var("?"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
CHRNA4
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses v1.0.0

In-Edges 2

p(HGNC:CHRNA4) hasVariant p(HGNC:CHRNA4, var("?")) View Subject | View Object

Appears in Networks:

path(MESH:Epilepsy) positiveCorrelation p(HGNC:CHRNA4, var("?")) View Subject | View Object

Mutations in nicotinic receptor subunits are linked to human disease, alpha4 and beta2 in some epilepsies, alpha7 in schizophrenia, and alpha5 in nicotine addiction; and each mutation ultimately manifests itself as an imbalance in the properties of neuronal circuits PubMed:21482353

Appears in Networks:

Out-Edges 2

p(HGNC:CHRNA4, var("?")) positiveCorrelation path(MESH:Epilepsy) View Subject | View Object

Mutations in nicotinic receptor subunits are linked to human disease, alpha4 and beta2 in some epilepsies, alpha7 in schizophrenia, and alpha5 in nicotine addiction; and each mutation ultimately manifests itself as an imbalance in the properties of neuronal circuits PubMed:21482353

Appears in Networks:

p(HGNC:CHRNA4, var("?")) increases path(HBP:"Autosomal Dominant Nocturnal Frontal Lobe Epilepsy") View Subject | View Object

Autosomal-dominant nocturnal frontal lobe epilepsy (ADNFLE) is caused by missense mutations in either the alpha4 or the beta2 subunit PubMed:21482353

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.