p(MGI:Cd163)
Interestingly, in both liver and spleen, the expression of the Hb-Hp receptor (CD163)29 was found to be fully suppressed at both the mRNA and protein levels (Figure 4C and D and Online Supplementary Figure S1B), suggesting a slowdown of Hb uptake in macrophages which may prevent excess iron overload. PubMed:28143953
Interestingly, in both liver and spleen, the expression of the Hb-Hp receptor (CD163)29 was found to be fully suppressed at both the mRNA and protein levels (Figure 4C and D and Online Supplementary Figure S1B), suggesting a slowdown of Hb uptake in macrophages which may prevent excess iron overload. PubMed:28143953
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.