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complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain"))

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A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways v1.0.0

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Out-Edges 3

complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) hasComponent p(HGNC:CDC37L1) View Subject | View Object

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complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) hasComponent p(INTERPRO:"Cdc37, N-terminal domain") View Subject | View Object

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complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) regulates complex(p(HGNC:ARAF), p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) View Subject | View Object

CDC37L1 lacks the very N terminus of CDC37, which is required for kinase interaction and the cellular function of CDC37 (Shao et al., 2003), and is able to mediate strong interaction with ARAF when fused to CDC37L1 (Figure S3B) PubMed:25036637

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.