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p(INTERPRO:"Cdc37, N-terminal domain")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Cdc37, N-terminal domain
Namespace
interpro
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/interpro-names.belns

Appears in Networks 1

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways v1.0.0

In-Edges 2

complex(p(HGNC:ARAF), p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) hasComponent p(INTERPRO:"Cdc37, N-terminal domain") View Subject | View Object

Appears in Networks:

complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) hasComponent p(INTERPRO:"Cdc37, N-terminal domain") View Subject | View Object

Appears in Networks:

Out-Edges 1

p(INTERPRO:"Cdc37, N-terminal domain") increases act(p(HGNC:CDC37)) View Subject | View Object

CDC37L1 lacks the very N terminus of CDC37, which is required for kinase interaction and the cellular function of CDC37 (Shao et al., 2003), and is able to mediate strong interaction with ARAF when fused to CDC37L1 (Figure S3B) PubMed:25036637

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.