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bp(GO:"axonal transport of mitochondrion")

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Entity

Name
axonal transport of mitochondrion
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 2

Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity v1.0.0

Caenorhabditis elegans models of tauopathy v1.0.0

In-Edges 2

a(HBP:"Tau aggregates") decreases bp(GO:"axonal transport of mitochondrion") View Subject | View Object

The velocity of mitochondrial transport in the pro-aggregant strain was lower than in wild-type (mean + SD ¼ 171 + 111 versus 256 + 117 nm/s), whereas the anti-aggregant strain (194 + 131 nm/ s) did not substantially differ from wild- type (Fig. 7D). PubMed:22611162

Appears in Networks:

composite(p(HBP:"4R tau", var("p.Lys280del")), p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met"))) decreases bp(GO:"axonal transport of mitochondrion") View Subject | View Object

As a result, the proaggregant lines showed a range of defects including paralysis, axonal degeneration of GABAergic and cholinergic motor neurons, presynaptic defects, synapse loss, and mitochondrial transport defects early in adulthood PubMed:29191965

Appears in Networks:

Out-Edges 0

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.