a(UNIPROT:Q9SEH4)
N-methyl-Δ1-pyrrolinium is synthesized from arginine and/ or ornithine, and is controlled by putrescine N-methyl transferase (PMT), which is the key enzyme in diverting metabolism towards the biosynthesis of nicotine and others alkaloids [12, 13]. PubMed:19165623
Experiments involving RNA-mediated gene silencing with transgenic Nicotiana plants have shown that a decrease in PMT expression levels can lead to low nicotine content PubMed:19165623
N-methyl-Δ1-pyrrolinium is synthesized from arginine and/ or ornithine, and is controlled by putrescine N-methyl transferase (PMT), which is the key enzyme in diverting metabolism towards the biosynthesis of nicotine and others alkaloids [12, 13]. PubMed:19165623
Down-regulation of PMT expression led to elevation of anatabine level in transgenic tobacco root lines and leaf tissues of regenerated tobacco plants PubMed:19165623
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.