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path(MESH:Apathy)

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Entity

Name
Apathy
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

Appears in Networks 1

Alzheimer's Disease: Targeting the Cholinergic System v1.0.0

In-Edges 2

a(MESH:"Cholinergic Neurons") decreases path(MESH:Apathy) View Subject | View Object

It has been postulated that the loss of cholinergic neurons and the consequent impairment in dopaminergic transmission could be the main factors underling AD-related psychiatric symptoms PubMed:26813123

Appears in Networks:
Annotations
MeSH
CA3 Region, Hippocampal
MeSH
Alzheimer Disease

path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Apathy) View Subject | View Object

In addition to cognitive alterations, psychiatric symptoms are frequently observed in AD patients, including apathy and depression PubMed:26813123

Appears in Networks:
Annotations
MeSH
CA3 Region, Hippocampal

Out-Edges 1

path(MESH:Apathy) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

In addition to cognitive alterations, psychiatric symptoms are frequently observed in AD patients, including apathy and depression PubMed:26813123

Appears in Networks:
Annotations
MeSH
CA3 Region, Hippocampal

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.