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bp(GO:cytolysis)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
cytolysis
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

a(MESH:"Complement Membrane Attack Complex") increases bp(GO:cytolysis) View Subject | View Object

Ultimately, activation of the complement cascade results in formation of the terminal complement complex C5b-9, the so-called membrane attack complex, and consequently a pore formation resulting in osmotic lysis of the target [71]. In the case of red blood cells, hemolysis will result. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

a(MESH:"Pore Forming Cytotoxic Proteins") increases bp(GO:cytolysis) View Subject | View Object

The earliest documented effect of PFTs is their ability to rapidly kill red blood cells through osmotic lysis. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Sepsis
Text Location
Review

Out-Edges 0

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.