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p(HGNC:CHI3L1)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
CHI3L1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 2

Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-b peptide and s levels: target engagement, tolerability and pharmacokinetics in humans v0.1.0

RelB/p50 complexes regulate cytokine-induced YKL-40 expression v1.0.0

In-Edges 4

a(PUBCHEM:11249342) decreases p(HGNC:CHI3L1) View Subject | View Object

A significant lowering of pro-inflammatory, C3 (86.9%) and microglial activation markers, MCP-1 (87.5%) and YKL-40 (72.7%), was evident. PubMed:22791904

Appears in Networks:

p(HGNC:RELA) causesNoChange p(HGNC:CHI3L1) View Subject | View Object

In these cells, basal expression of YKL-40 is RelB-, p65-, and STAT3-independent, implicating other unknown factors. PubMed:25681350

Appears in Networks:
Annotations
Cell Ontology (CL)
chondrocyte

p(HGNC:RELB) causesNoChange p(HGNC:CHI3L1) View Subject | View Object

In these cells, basal expression of YKL-40 is RelB-, p65-, and STAT3-independent, implicating other unknown factors. PubMed:25681350

Appears in Networks:
Annotations
Cell Ontology (CL)
chondrocyte

p(HGNC:STAT3) causesNoChange p(HGNC:CHI3L1) View Subject | View Object

In these cells, basal expression of YKL-40 is RelB-, p65-, and STAT3-independent, implicating other unknown factors. PubMed:25681350

Appears in Networks:
Annotations
Cell Ontology (CL)
chondrocyte

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.