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path(MESH:"beta-Thalassemia")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
beta-Thalassemia
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 5

a(CHEBI:heme) positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

The consequences of heme toxicity can be appreciated in hemolytic diseases such as β-thalassemia, sickle-cell disease (SCD), ischemia-reperfusion (IR), and malaria (Katori et al., 2002; Pamplona et al., 2007;Vinchi et al., 2013). PubMed:24904418

Appears in Networks:
Annotations
Text Location
Review

path(HP:"Deep venous thrombosis") positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(HP:"Portal vein thrombosis") positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"Pulmonary Embolism") positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:Hemolysis) positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

SCD and β-thalassemia are genetic diseases associated to erythrocytes that are prone to lysis due to defective Hb production (Heinle and Read, 1948; Pauling et al., 1949; Ingram, 1957; discussed later). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Rhabdomyolysis
Text Location
Review

Out-Edges 5

path(MESH:"beta-Thalassemia") positiveCorrelation a(CHEBI:heme) View Subject | View Object

The consequences of heme toxicity can be appreciated in hemolytic diseases such as β-thalassemia, sickle-cell disease (SCD), ischemia-reperfusion (IR), and malaria (Katori et al., 2002; Pamplona et al., 2007;Vinchi et al., 2013). PubMed:24904418

Appears in Networks:
Annotations
Text Location
Review

path(MESH:"beta-Thalassemia") positiveCorrelation path(MESH:Hemolysis) View Subject | View Object

SCD and β-thalassemia are genetic diseases associated to erythrocytes that are prone to lysis due to defective Hb production (Heinle and Read, 1948; Pauling et al., 1949; Ingram, 1957; discussed later). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Rhabdomyolysis
Text Location
Review

path(MESH:"beta-Thalassemia") positiveCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"beta-Thalassemia") positiveCorrelation path(HP:"Deep venous thrombosis") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"beta-Thalassemia") positiveCorrelation path(HP:"Portal vein thrombosis") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.