path(MESH:"Pulmonary Embolism")
Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933
The increased risk of thrombosis in patients who undergo a splenectomy is important. About 22 000 splenectomies are still conducted annually for all causes in the United States and splenectomized patients have a 22-fold increased rate of being hospitalized for deep vein thrombosis or pulmonary embolism (Kristinsson et al, 2014). PubMed:25307023
Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933
Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023
We hypothesize acute moderate to severe PE causes turbulent flow across the tricuspid and pulmonic valves and in the pulmonary tree, causing rupture of a small percentage of red cells in or immediately proximal to or within the pulmonary vascular tree. PubMed:26337933
Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933
Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023
The increased risk of thrombosis in patients who undergo a splenectomy is important. About 22 000 splenectomies are still conducted annually for all causes in the United States and splenectomized patients have a 22-fold increased rate of being hospitalized for deep vein thrombosis or pulmonary embolism (Kristinsson et al, 2014). PubMed:25307023
Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933
We hypothesize acute moderate to severe PE causes turbulent flow across the tricuspid and pulmonic valves and in the pulmonary tree, causing rupture of a small percentage of red cells in or immediately proximal to or within the pulmonary vascular tree. PubMed:26337933
BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.
If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.