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a(MESH:Arginase)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Arginase
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

a(HM:"Erythrocytes, lysed") increases a(MESH:Arginase) View Subject | View Object

In addition, lysed erythrocytes release arginase, which catalyzes the conversion of arginine, the substrate for NO synthesis, to ornithine. PubMed:29929138

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Hemoglobinuria, Paroxysmal
Text Location
Discussion

a(MESH:"Erythrocytes, Abnormal") increases a(MESH:Arginase) View Subject | View Object

Damaged RBCs also release arginase that cleaves L-arginine, a substrate for NO production [29]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
Text Location
Review

rxn(reactants(a(CHEBI:arginine)), products(a(CHEBI:ornithine))) positiveCorrelation a(MESH:Arginase) View Subject | View Object

In addition, lysed erythrocytes release arginase, which catalyzes the conversion of arginine, the substrate for NO synthesis, to ornithine. PubMed:29929138

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Hemoglobinuria, Paroxysmal
Text Location
Discussion

Out-Edges 1

a(MESH:Arginase) positiveCorrelation rxn(reactants(a(CHEBI:arginine)), products(a(CHEBI:ornithine))) View Subject | View Object

In addition, lysed erythrocytes release arginase, which catalyzes the conversion of arginine, the substrate for NO synthesis, to ornithine. PubMed:29929138

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Hemoglobinuria, Paroxysmal
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.