a(MESH:"Cerebrospinal Fluid")
First, in ageing, and particularly in AD, CSF production by the choroid plexus is reduced, as shown by decreased water secretion into the ventricles via AQP1 water channels. PubMed:26195256
In addition, Aβ deposition in CP also blocks CSF production in AD (Serot et al. 2012). PubMed:29626319
CSF is produced mainly by choroid plexus PubMed:29626319
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