Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Appears in Networks 1

In-Edges 0

Out-Edges 5

complex(a(GO:"proteasome complex"), p(HGNC:BAG6)) increases deg(p(MESH:Proteins, pmod(HBP:misfolding))) View Subject | View Object

Because Bag6 interacts with both E3 ligases as well as the proteasome [57,58,60], it may promote both the ubiquitination and delivery of misfolded proteins to the proteasome while preventing their aggregation PubMed:24457024

complex(a(GO:"proteasome complex"), p(HGNC:BAG6)) decreases bp(HBP:"protein aggregation") View Subject | View Object

Because Bag6 interacts with both E3 ligases as well as the proteasome [57,58,60], it may promote both the ubiquitination and delivery of misfolded proteins to the proteasome while preventing their aggregation PubMed:24457024

complex(a(GO:"proteasome complex"), p(HGNC:BAG6)) increases bp(GO:"protein ubiquitination") View Subject | View Object

Because Bag6 interacts with both E3 ligases as well as the proteasome [57,58,60], it may promote both the ubiquitination and delivery of misfolded proteins to the proteasome while preventing their aggregation PubMed:24457024

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.