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  3. p(HGNC:PRTN3)

p(HGNC:PRTN3)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
PRTN3
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 2

Activation and regulation of the inflammasomes v1.0.0

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

p(HGNC:SERPINA1) decreases p(HGNC:PRTN3) View Subject | View Object

The main function of A1AT is to inhibit neutrophil elastase and proteinase 3. PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Serum
MeSH
Malaria
Text Location
Discussion

Out-Edges 1

p(HGNC:PRTN3) increases act(p(HGNC:IL1B)) View Subject | View Object

Indeed, a number of non-caspase proteases such as proteinase 3 have the ability to activate IL-1β in an inflammasome-independent manner11. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Interleukin signaling subgraph

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.