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p(MGI:Hamp)

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Entity

Name
Hamp
Namespace
mgi
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/mgi-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 4

a(CHEBI:"lead nitrate") positiveCorrelation p(MGI:Hamp) View Subject | View Object

With respect to the absence of Hri, there were slightly greater serum iron concentrations, total splenic iron content, and hepatic hepcidin expression level in Hri-deficient mice, relative to those in Wt mice (Figure 8A−C). PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythroid progenitor cell
MeSH
Liver
Text Location
Results

a(CHEBI:"lead nitrate") positiveCorrelation p(MGI:Hamp) View Subject | View Object

However, Pb exposure induced hepatic hepcidin expression by nearly 2- fold in Ko + Pb mice with a resultant significant increase of total splenic iron, compared to that in Ko − Pb mice (Figure 8 B and C; P < 0.05). PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythroid progenitor cell
MeSH
Liver
Text Location
Results

complex(p(MGI:Hamp), p(MGI:Slc40a1)) hasComponent p(MGI:Hamp) View Subject | View Object

Appears in Networks:

p(MGI:Eif2ak1) negativeCorrelation p(MGI:Hamp) View Subject | View Object

Moreover, loss of Hri gave rise to hepatic hepcidin induction, associated with iron retention in spleens. PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Spleen
Text Location
Discussion

Out-Edges 3

p(MGI:Hamp) positiveCorrelation a(CHEBI:"lead nitrate") View Subject | View Object

With respect to the absence of Hri, there were slightly greater serum iron concentrations, total splenic iron content, and hepatic hepcidin expression level in Hri-deficient mice, relative to those in Wt mice (Figure 8A−C). PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythroid progenitor cell
MeSH
Liver
Text Location
Results

p(MGI:Hamp) positiveCorrelation a(CHEBI:"lead nitrate") View Subject | View Object

However, Pb exposure induced hepatic hepcidin expression by nearly 2- fold in Ko + Pb mice with a resultant significant increase of total splenic iron, compared to that in Ko − Pb mice (Figure 8 B and C; P < 0.05). PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythroid progenitor cell
MeSH
Liver
Text Location
Results

p(MGI:Hamp) negativeCorrelation p(MGI:Eif2ak1) View Subject | View Object

Moreover, loss of Hri gave rise to hepatic hepcidin induction, associated with iron retention in spleens. PubMed:25411909

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Spleen
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.