1. Catalog
  2. Nodes
  3. complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1))

complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Carboxy terminus heat shock protein 70 interacting protein reduces tau-associated degenerative changes v1.0.0

In-Edges 1

p(HGNC:STUB1) increases complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1)) View Subject | View Object

Either of these domains could be critical for degradation of tau since ubiquitination targets proteins for degradation and CHIP is known to interact with full-length tau in a complex with Hsc70/Hsp70 and poly-ubiquitinated tau [17]. PubMed:25374103

Appears in Networks:

Out-Edges 3

complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1)) hasComponent p(HGNC:HSPA8) View Subject | View Object

Appears in Networks:

complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1)) hasComponent p(HGNC:MAPT, pmod(Ub)) View Subject | View Object

Appears in Networks:

complex(p(HGNC:HSPA8), p(HGNC:MAPT, pmod(Ub)), p(HGNC:STUB1)) hasComponent p(HGNC:STUB1) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.