Tau annular protofibrils

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: Tau annular protofibrils
Namespace: HBP
Namespace Version: 20181023
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/3074b85b858455d8eeb76cfcdef685ced19bbe11/export/hbp-names.belns

Appears in Networks 1

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage from Shafiei et al., 2017

In-Edges 2

a(HBP:"Tau oligomers") increases a(HBP:"Tau annular protofibrils") View Subject | View Object

The study discovered that APFs form after tau oligomer formation and bypass higher NFT aggregate formation PubMed:28420982

Appears in Networks:

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Annotations

MeSH: Extracellular Space
Confidence: High
MeSH: Neurons
MeSH: Alzheimer Disease

path(MESH:Tauopathies) association a(HBP:"Tau annular protofibrils") View Subject | View Object

Hence, tau APFs may play a significant role in tauopathies by linking pore formation to cell death PubMed:28420982

Appears in Networks:

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Annotations

MeSH: Extracellular Space
Confidence: High
MeSH: Neurons
MeSH: Alzheimer Disease

Out-Edges 1

a(HBP:"Tau annular protofibrils") association path(MESH:Tauopathies) View Subject | View Object

Hence, tau APFs may play a significant role in tauopathies by linking pore formation to cell death PubMed:28420982

Appears in Networks:

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Annotations

MeSH: Extracellular Space
Confidence: High
MeSH: Neurons
MeSH: Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.