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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:heme) positiveCorrelation path(MESH:"Lung Injury") View Subject | View Object

These data indicate that the increased severity of bacterial lung injury secondary to massive resuscitation with stored RBCs is heme-dependent. PubMed:29522519

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act(p(MGI:Tlr4)) negativeCorrelation path(MESH:"Lung Injury") View Subject | View Object

These data demonstrate that TLR4 signaling plays a role in heme-induced exacerbation of lung bacterial infection secondary to TH followed by massive resuscitation with stored RBCs. PubMed:29522519

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Out-Edges 2

path(MESH:"Lung Injury") positiveCorrelation a(CHEBI:heme) View Subject | View Object

These data indicate that the increased severity of bacterial lung injury secondary to massive resuscitation with stored RBCs is heme-dependent. PubMed:29522519

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path(MESH:"Lung Injury") negativeCorrelation act(p(MGI:Tlr4)) View Subject | View Object

These data demonstrate that TLR4 signaling plays a role in heme-induced exacerbation of lung bacterial infection secondary to TH followed by massive resuscitation with stored RBCs. PubMed:29522519

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.