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bp(GO:"synapse maturation")

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Entity

Name
synapse maturation
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 2

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses v1.0.0

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 2

p(HGNC:LYNX1) negativeCorrelation bp(GO:"synapse maturation") View Subject | View Object

Neuronal maturation and loss of synaptic lability appear to be correlated with the onset of lynx1 expression PubMed:21482353

Appears in Networks:

p(HGNC:ARC) regulates bp(GO:"synapse maturation") View Subject | View Object

This and numerous related findings suggest that degradation of certain critical proteins by the UPS is required during long-term memory formation. One of these proteins is arc, a negative regulator of synaptic strength that promotes the internalization of AMPA receptors and is degraded via the E3 ligase, UBE3A (Greer et al. 2010). PubMed:22908190

Appears in Networks:

Out-Edges 1

bp(GO:"synapse maturation") negativeCorrelation p(HGNC:LYNX1) View Subject | View Object

Neuronal maturation and loss of synaptic lability appear to be correlated with the onset of lynx1 expression PubMed:21482353

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.