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p(HGNC:HIST1H3B)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
HIST1H3B
Namespace
hgnc
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/hgnc-names.belns

Appears in Networks 1

Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome v1.0.0

In-Edges 3

a(PUBCHEM:9832404) increases p(HGNC:HIST1H3B) View Subject | View Object

In the mature cerebral cortex, only histone cluster 1 H3 family member B (Hist1h3b), which was one of the major transcripts downregulated in the hippocampi of 5-month-old Adnp+/–mice compared with Adnp+/+ mice (6, 17), was found here to be downregulated in the female Adnp+/– mouse. This effect was now shown to be reversed by NAP treatment (Figure 4B). PubMed:30106381

Appears in Networks:
Annotations
MeSH
Cerebral Cortex
MeSH
Hippocampus
Gender
Female

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases p(HGNC:HIST1H3B) View Subject | View Object

In the mature cerebral cortex, only histone cluster 1 H3 family member B (Hist1h3b), which was one of the major transcripts downregulated in the hippocampi of 5-month-old Adnp+/–mice compared with Adnp+/+ mice (6, 17), was found here to be downregulated in the female Adnp+/– mouse. This effect was now shown to be reversed by NAP treatment (Figure 4B). PubMed:30106381

Appears in Networks:
Annotations
MeSH
Cerebral Cortex
MeSH
Hippocampus
Gender
Female

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) regulates p(HGNC:HIST1H3B) View Subject | View Object

Female cortical Hist1h3b was found to be regulated only by the Adnp+/– genotype. PubMed:30106381

Appears in Networks:
Annotations
Gender
Female

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.