1. Catalog
  2. Nodes
  3. r(HGNC:TFEB)

r(HGNC:TFEB)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
TFEB
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading v1.0.0

In-Edges 2

path(MESH:"Cognitive Dysfunction") positiveCorrelation r(HGNC:TFEB) View Subject | View Object

Transcriptional levels of TFEB and several of its well-known lysosomal targets were stratified by no demen- tia, mild cognitive impairment, and dementia,these transcript levels positively correlate with cognitive decline PubMed:30108137

Appears in Networks:

path(MESH:"Frontotemporal Dementia") increases r(HGNC:TFEB) View Subject | View Object

. In addition, human brains diagnosed with frontotemporal demen- tia (FTD) demonstrated an increase in transcriptional levels of TFEB and TFEB lysosomal target gene LAMP1 PubMed:30108137

Appears in Networks:

Out-Edges 1

r(HGNC:TFEB) positiveCorrelation path(MESH:"Cognitive Dysfunction") View Subject | View Object

Transcriptional levels of TFEB and several of its well-known lysosomal targets were stratified by no demen- tia, mild cognitive impairment, and dementia,these transcript levels positively correlate with cognitive decline PubMed:30108137

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.