bp(GO:"regulation of vascular permeability")
Free heme is lipophilic and intercalates into the membrane of endothelial cells increasing vascular permeability and ICAM-1, VCAM-1, and E-selectin expression (19). PubMed:19276082
Heme injection in mice leads to vascular permeability, leukocyte migration from the intravascular environment to tissues and increase of acute-phase proteins (Lyoumi et al., 1999; Wagener et al., 2001b), hallmarks of acute inflammation. PubMed:24904418
Free heme is lipophilic and intercalates into the membrane of endothelial cells increasing vascular permeability and ICAM-1, VCAM-1, and E-selectin expression (19). PubMed:19276082
Heme injection in mice leads to vascular permeability, leukocyte migration from the intravascular environment to tissues and increase of acute-phase proteins (Lyoumi et al., 1999; Wagener et al., 2001b), hallmarks of acute inflammation. PubMed:24904418
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.