bp(MESH:"Bacterial Load") negativeCorrelation a(CHEBI:quinine)
Following induction of E. coli peritonitis in wild-type mice, quinine treatment did not affect plasma heme levels, but did lead to a reduction in bacterial counts in blood and liver (Fig. 8f,g and Supplementary Fig. 8g,h), thereby restoring the bacterial clearance capacity of heme-treated mice.
BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.
If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.