act(a(MESH:"Blood-Brain Barrier")) association p(HGNC:PPIA)

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PubMed:26195256

Third, ApoE4 is also associated with lower antioxidant activity than other ApoE isoforms,154,155 and it mediates BBB breakdown through a proinflammatory pathway involving cyclophilin A in pericytes.

Related Edges 2

• p(HBP:"APOE e4") regulates a(MESH:"Blood-Brain Barrier")
• p(HGNC:PPIA) association act(a(MESH:"Blood-Brain Barrier"))

MeSH

Hippocampus

MeSH

Temporal Lobe

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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