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bone marrow cell

Name
bone marrow cell
Namespace Keyword
Cell
Namespace
Cell Ontology (CL)
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell/cell-20170511.belanno

Sample Annotated Edges 5

a(CHEBI:"iron(2+)") positiveCorrelation path(MESH:"Porphyria, Erythropoietic") View Subject | View Object

Using isolated duodenal loops to measure the transepithelial iron transport, we found that CEP mice presented a higher rate of iron absorption than the WT mice, although the differences between the area under the curves did not reach statistical significance (Figure 3D). PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
bone marrow cell
MeSH
Duodenum
MeSH
Porphyria, Erythropoietic
Text Location
Results

a(CHEBI:"iron(2+)") positiveCorrelation path(MESH:"Porphyria, Erythropoietic") View Subject | View Object

Serum iron was also increased in CEP mice, but this did not lead to elevated Tf saturation because Tf was also significantly increased, which is reminiscent of iron deficiency anemia and facilitates iron delivery to a larger number of erythroblasts (Table 1 and Figure 3G). PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
bone marrow cell
MeSH
Serum
MeSH
Porphyria, Erythropoietic
Text Location
Results

p(MGI:Slc40a1) positiveCorrelation path(MESH:"Porphyria, Erythropoietic") View Subject | View Object

In addition, we observed an increase of ferroportin protein expression in duodenal enterocytes (Figure 3E and F). PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
bone marrow cell
MeSH
Duodenum
MeSH
Porphyria, Erythropoietic
Text Location
Results

p(MGI:Ftl1) positiveCorrelation path(MESH:"Porphyria, Erythropoietic") View Subject | View Object

As expected, serum ferritin was significantly increased in CEP mice (Figure 3H). PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
bone marrow cell
MeSH
Serum
MeSH
Porphyria, Erythropoietic
Text Location
Results

p(MGI:Trf) positiveCorrelation path(MESH:"Porphyria, Erythropoietic") View Subject | View Object

Serum iron was also increased in CEP mice, but this did not lead to elevated Tf saturation because Tf was also significantly increased, which is reminiscent of iron deficiency anemia and facilitates iron delivery to a larger number of erythroblasts (Table 1 and Figure 3G). PubMed:28143953

Appears in Networks:
Annotations
Cell Ontology (CL)
bone marrow cell
MeSH
Serum
MeSH
Porphyria, Erythropoietic
Text Location
Results

Showing 5 of 12 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.